Welcome readers of Pharmaceutical Processing
Pharmaceutical Mixing Equipment
Today’s pharmaceutical processes involve a large range of liquid blending operations, with methods ranging from simple liquid blending or heat transfer, to gum and stabilizer dispersions, to complex emulsion creation. Our sanitary designs meet tough hygienic and safety standards for GMP facilities. Our pharmaceutical batch mixers, inline mixing and milling equipment, and powder induction systems are constructed of FDA-approved materials and many are 3-A certified and comply with strict cGMP requirements. Factory Acceptance Testing (FAT), QA and full validation documentation packages are available.
Admix has hundreds of global equipment installations across all process levels within the pharmaceutical and biotechnology industries. Our mixing expertise combined with our understanding of common ingredients and APIs allows us to offer solutions that improve production with effective mixing, reduced horsepower, and optimized capital costs.
Some applications our sanitary mixers have been used for include:
- Oral suspensions
- Saline solutions
- Cough syrups and elixirs
- Solid dose coatings
- Gel caps
- Therapeutic creams and lotions
The Benchmix series of lab mixers offers sanitary, all stainless steel benchtop laboratory mixers designed for product development, simulation, and scale up for batches up to 5 gallons (20 liters).
For small production runs up to 20 gallons (75 liters), the Rotosolver RS-02 pilot plant floor model is also available. See how Admix offers these predictable, repeatable results all the way up to 10,000 gallons with a process assurance warranty on both Benchmix process results as well as through our free lab testing service.
The Rotosolver high shear mixer is our flagship product with thousands of installations at food and beverage processing plants around the world. If your production line requires 100% wetting out of powders, and an easy-to-clean design that meets 3-A sanitary requirements, the Rotosolver is the solution. The Rotosolver design includes two additional shear zones providing higher overall shear rates, improved dispersion, and reduced energy consumption for volumes up to 10,000 gallons.
The Rotosolver outperforms competitors in key performance areas. For various applications, it has delivered up to:
- 50% less energy consumption
- 600% higher flow rates
- 20% higher tip speeds
- 6 times more throughput than conventional mixers
The Fastfeed powder induction and dispersion system inducts, wets, and disperses ingredients instantly eliminating agglomerates. Proteins, gums, starches, vitamins, fiber, sweeteners, stabilizers, emulsifiers, flavors, and colors are dispersed at rates up to 450 pounds per minute in a single pass. It consumes up to 70% less energy than conventional tank mixers and batch-to-batch inconsistencies are eliminated as powders are introduced at the same rate every time. Batch times and air entrainment are also reduced because powders. Dust from dumping powders into open top tanks is also eliminated.Operator safety is also enhanced as powders are added from the safety of floor level. See how the Fastfeed can improve your product quality in half the time with less energy.
The Dynashear inline high speed emulsifier disperses gums, stabilizers, proteins and sweeteners in a single pass delivering batch times as low as 3-5 minutes and less air entrainment. With flow rates up to 175 GPM, the 3-A compliant Dynashear delivers smooth product every time with no fisheyes or agglomerates. The two-stage rotor/stator action allows processors to run longer and CIP less frequently. When installed upstream of inline strainers or HTST balance tanks, the Dynashear improves your process, preventing clogged strainers and extending the life of pumps, valves, and seals. Lower your maintenance costs and total cost of ownership today!
Common Pharmaceutical Processing Problems Solved
- Slow batch times
- Lumps, clumps, or fisheyes
- Clogged strainers
- Inconsistent powder incorporation
- Batch-to-batch inconsistencies
- Inefficiencies dispersing more powder into less water
- Air entrainment
- Operator injuries/safety considerations
See how the Rotosolver high shear mixer quickly and efficiently disperses carbomer/Carbopol, a popular agent in pharmaceuticals, in less than 10 minutes.