Today's pharmaceutical processes involve a large range of liquid blending operations. Methods range from simple liquid blending or heat transfer challenges, to gum and stabilizer dispersions, to complex emulsion creation.
We have solutions across all process levels within the pharmaceutical and biotechnology industries. Our mixing expertise combined with our understanding of common ingredients and APIs allows us to offer solutions that improve production with effective mixing, reduced horsepower and optimized capital costs.
Our sanitary designs meet tough hygienic and safety standards for GMP facilities. They are constructed of FDA-approved materials and many are 3-A certified and comply with strict cGMP requirements. Factory Acceptance Testing (FAT), QA and full validation documentation packages are available.
Let our application engineers recommend a customized pharmaceutical mixing solution for you or have your ingredient tested for free in our pilot lab.
Absolutely. All Admix equipment is scalable, and we consider many more scaling parameters than just traditional horsepower per unit volume. Our evaluations are detailed and we are so confident in our scaling that we provide a process assurance warranty with every quote. We are happy to work with your R&D department to define lab scale testing that precisely matches plant performance with existing production equipment.
All our equipment is designed with CIP processes in mind. For pharmaceutical processes we go further, expecting SIP to also occur. We follow cGxP methods for design and manufacturing, along with ASME-BPE codes to provide simple-to-clean equipment. Furthermore, we often work with end users to implement the most successful cleaning protocols.
The Rotosolver offers a unique blend of high shear and high flow, often replacing the need for secondary agitation in a vessel using a rotor/stator mixer. Except in the most extreme emulsification processes, the energy-saving Rotosolver can replace traditional high horsepower rotor/stator mixers, which require more power. The capital, operating and maintenance costs are all lower as a result.
What’s the largest capacity tank the Rotosolver can handle? What about the RotoMAXX II?
Rotosolver mixers have been used on vessels well over 5,000 gallons. Our teams are always aware of maximum volume flexibility and minimum heel volumes (waste) for a process and consider smaller vessels with rapid process times or the installation of an inline high shear mixer to ensure all product receives the necessary mixing energy.
The RotoMAXX II uses a unique bearing frame assembly with a helical bevel gear reducer to handle tank volumes of 60,000 gallons and beyond. With a broad range of available speed ratios and in-house design and fabrication of impellers, we determine the best combination to meet your existing needs and to handle future process and recipe changes without requiring complete equipment replacement.
These workhorses break down tough fisheyes in a single pass, and deagglomerate a fluid stream to save filter cleaning and wasted raw material. Designed to run 24/7, both DynaShear and the Boston Shearmill meet 3-A sanitary standard #36-01.We need simple tank agitation at various volumes. What does Admix offer?
While dispersing hard-to-wet powders for pill coatings, how can I avoid rafting on the top of the vessel?